RNA Details
Disease Name
renal interstitial fibrosis
Tissue
kidney
RNA Symbol
mir-133b
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
NA
Target
MiR-133b
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
Title
Regulation of connective tissue growth factor expression by miR-133b for the treatment of renal interstitial fibrosis in aged mice with unilateral ureteral obstruction
Year
2021
Function
"MiR-133b exerted targeted inhibitory effects on CTGF expression, which consequently reduced TGF-BETA1-induced epithelial-mesenchymal transition (EMT) of HK2 cells and renal interstitial fibrosis in aged mice with unilateral ureteral obstruction (UUO)."